SULPHONAMIDES IN GONORRHOEA

Therapeutic trial of trimethoprim as a potentiator of sulphonamides in gonorrhoea.

Trimethoprim (2,4,diamino-5-(3',4',5'-trimethoxybenzyl) pyrimidine) is an antifolic acid agent developed by workers at the Wellcome Research Laboratories (Hitchings, Elion, Falco, Russell, Sherwood, and Vanderwerff, 1950a, b). It was found to inhibit the enzyme dihydrofolic acid reductase in bacteria with little or none of this activity against the corresponding enzymes of mammalian species (Hi...

Sulphonamides in Undulant Fever

Sulphonamides in Urine

Sulphonamides in Topical Application

The Sulphonamides in Bacillary Dysentery